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Prescription weight-loss medicines may help some people who haven't been able to lose weight that you don't need a prescription for are appetite suppressants and water-loss pills. Liraglutide (Saxenda) is given as a shot once a day.
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As part of their standard slimdown program, many weight loss clinics offer B12 supplementation (either as a shot or a pill) to boost energy and metabolism. However, despite this common practice, one expert notes that extra B12 probably won’t help much for weight loss or energy unless you are deficient ( 6 ).
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